---
title: Epidural Stimulation Study Sees Amazing Results for Paralyzed People
description: It's hard not to get excited about epidural stimulation with all the positive research results being released from dozens of labs worldwide, and a recent study released by the ongoing E-STAND trial and the University of Minnesota only makes us more excited. In this recent study, they were able to
image: https://www.spinalcord.com/hubfs/Stock%20images/Doctors%20sitting%20around%20the%20table%20and%20interpreting%20x-ray%20image.jpeg
---

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# Epidural Stimulation Study Sees Amazing Results for Paralyzed People

 Author: [Spinal Cord Team](https://www.spinalcord.com/meet-our-authors)

 Publish Date: December 08, 2020

It's hard not to get excited about epidural stimulation with all the positive research results being released from dozens of labs worldwide, and a recent study released by the ongoing [E-STAND trial](https://www.estand.org/blog/) and the University of Minnesota only makes us more excited. In this recent study, they were able to prove that epidural stimulation also works on people who have been injured for several years.

Up until now, newly-injured patients were often used, or at least people in their 20s. Researchers decided to choose two women in their 50s and 60s and 5 to 10 years post injury for the study, in the hopes that they could expand the population that [epidural stimulation](https://www.spinalcord.com/blog/what-to-know-epidural-stimulation-spinal-cord-injury) hypothetically could be used on. Both women had a spinal cord stimulator implanted near their injury site, which can then be turned on and off with a remote.

Thankfully it was a massive success. Both participants in the study saw immediate results in functional movement and automatic functions, such as [bladder and bowel control and sexual function](https://www.spinalcord.com/bladder-bowel-and-sexual-functions-after-sci?hsCtaTracking=e0f6ce52-5cde-4e6d-9773-d03b397c6c40%7C8ddcf683-056a-41d2-8ebb-01b3c21e89ee). Now several months post-injury, both patients can now move their legs, albeit minimally, but they can do so by their own volition, which is a huge change from before. They are both ASIA A injuries, which means they had no movement or sensation below their level of injury before the trial.

Needless to say, the surgeons involved in the trial are extremely excited.

> “Enabling someone to move her legs more than 10 years after being paralyzed from spinal cord injury has been one of the greatest moments of my career," said Uzma Samadani, MD, PhD, Associate Professor in the Department of Neurosurgery University of Minnesota Medical School and Neurosurgeon with Hennepin Healthcare.”

Considering that people with long-term [paralysis ](https://www.spinalcord.com/paralysis)have never been given any kind of hope until now, this is a huge, historical event. In fact, we are confused as to why more news outlets aren't covering this. We realize the world is a bit crazy these days, but people with paralysis are literally moving again and seeing abilities return that doctors never thought could happen. Miracles are at work.

The good news is that you can follow the study closely. The researchers are very transparent. There is an active blog updating the world on the trial’s latest activities, appearances in the news, as well as videos directly from participants in the study sharing updates of their improved abilities. For example, if you visit [Dr. David Darrow’s YouTube channel](https://www.youtube.com/channel/UC7hthbzjESq_CyouHEiCdxA), one of the trial’s leads, you can watch a video of a participant moving their leg with the help of a skateboard attached underneath:

The next obvious question is: when will this be available to the public? Unfortunately the researchers in the study caution the public to be patient, as there is no timeline yet as to when this will be available to the over 290,000 people in the United States living with a [spinal cord injury](https://www.spinalcord.com/spinal-cord-injury). Hopefully, because of these overwhelmingly positive results, they will get it pushed through quickly once requested to do so by the FDA.

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**Topics:** Technology & Advancements, Research, Paralysis

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 The authors of Spinalcord.com are made up of attorneys, those in the medical field, and survivors of spinal cord injuries or traumatic brain injuries. Learn more about our team of authors including a brief biography that explains how they impact the SCI and TBI community. 

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### Spinal Cord Injury

- [Types of Spinal Cord Injuries](https://www.spinalcord.com/types-of-spinal-cord-injuries)
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### Brain Injury

- [Types of Brain Injuries](https://www.spinalcord.com/types-of-traumatic-brain-injury)
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```json
{
  "@context" : "http://schema.org",
  "@type" : "Article",
  "articleBody" : "The spinal cord is a vital part of the human body. As the vehicle responsible for carrying messages from the brain to the rest of the body and back again, even the smallest interference can be detrimental. Following a traumatic <A href=\"/spinal-cord-injury\" rel=\"noopener\" target=\"_blank\"><SPAN style=\"font-weight: 400;\">spinal cord injury</SPAN></A>, this bundle of nerves can become bruised, also known as <A href=\"//www.spinalcord.com/blog/contusion-vs.-concussion-understanding-the-difference\">a contusion.</A> Because of the nature of the nervous system, any interference can constitute a serious spinal contusion, but these facts will help you dissect all of the information from the medical professionals.</P>\n\n<H2><STRONG>What Is a Spinal Contusion?</STRONG></H2>\n<IMG src=\"https://www.spinalcord.com/hs-fs/hubfs/Blog-Images/Signs-of-a-spinal-contusion-title-image-min.jpg?width=300&amp;name=Signs-of-a-spinal-contusion-title-image-min.jpg\" alt=\"Signs-of-a-spinal-contusion-title-image\" width=\"300\" style=\"width: 300px; float: right; margin: 0px 0px 10px 10px;\" srcset=\"https://www.spinalcord.com/hs-fs/hubfs/Blog-Images/Signs-of-a-spinal-contusion-title-image-min.jpg?width=150&amp;name=Signs-of-a-spinal-contusion-title-image-min.jpg 150w, https://www.spinalcord.com/hs-fs/hubfs/Blog-Images/Signs-of-a-spinal-contusion-title-image-min.jpg?width=300&amp;name=Signs-of-a-spinal-contusion-title-image-min.jpg 300w, https://www.spinalcord.com/hs-fs/hubfs/Blog-Images/Signs-of-a-spinal-contusion-title-image-min.jpg?width=450&amp;name=Signs-of-a-spinal-contusion-title-image-min.jpg 450w, https://www.spinalcord.com/hs-fs/hubfs/Blog-Images/Signs-of-a-spinal-contusion-title-image-min.jpg?width=600&amp;name=Signs-of-a-spinal-contusion-title-image-min.jpg 600w, https://www.spinalcord.com/hs-fs/hubfs/Blog-Images/Signs-of-a-spinal-contusion-title-image-min.jpg?width=750&amp;name=Signs-of-a-spinal-contusion-title-image-min.jpg 750w, https://www.spinalcord.com/hs-fs/hubfs/Blog-Images/Signs-of-a-spinal-contusion-title-image-min.jpg?width=900&amp;name=Signs-of-a-spinal-contusion-title-image-min.jpg 900w\" sizes=\"(max-width: 300px) 100vw, 300px\"/>\n<P>Much like any other bruise, a contusion can cause bleeding from local blood vessels and inflammation which, rather<I><SPAN style=\"font-weight: 400;\"> unlike</SPAN></I> bruises on other parts of the body, can have serious negative impacts on the spinal cord itself. Because the<A href=\"/blog/contusion-vs.-concussion-understanding-the-difference\" rel=\"noopener\" target=\"_blank\"> “blood must clot to stop the bleeding”</A>a bruise results from contusions also increase cardiovascular risks.</P>\n<P>For example, the swelling a contusion can cause will often disrupt nerve impulses that travel from the brain to the body through the spinal cord, and the severity of this will depend upon the level of injury. Unlike a concussion, a contusion would not cause unconsciousness or a ‘blackout’, but instead cause the patient to feel a numbness or tingling in the extremities.</P>\n<P>A contusion can cause spinal compression, which happens when there is pressure on the spinal cord. This can go on to cause an array of <A href=\"http://www.hopkinsmedicine.org/healthlibrary/conditions/nervous_system_disorders/spinal_cord_compression_134,13/\" rel=\"noopener\" target=\"_blank\">physical symptoms</A> such as loss of sensation in the feet, inability to use the hands and loss of sexual ability. It must be noted that not all contusions cause spinal compression, and not all spinal compression is caused by a contusion, although they do often connect this way.</P>\n<H2><STRONG>Warning Signs of a Serious Spinal Contusion to Watch For</STRONG></H2>\n<P>Firstly, doctors will try and establish what area or limb the injury has affected. Spinal contusions most often “affect the upper extremities bilaterally and also sometimes involve the lower extremities,” <A href=\"http://www.healio.com/orthopedics/journals/ortho/2012-1-35-1/%7B7b1ed5f6-d6ca-435e-b69a-dba8a6d7c3c0%7D/spinal-cord-contusions\" rel=\"noopener\" target=\"_blank\">according to Dr. Wong</A>, an orthopedic physician.</P>\n<P>Symptoms include “numbness, tingling, [or] electric shock-like sensations and burning in the extremities,” <A href=\"http://www.aans.org/patient%20information/conditions%20and%20treatments/spinal%20cord%20injury.aspx\">(American Association of Neurological Surgeons, 2016)</A>. Generally falling into the category of “spinal trauma” there are many symptoms which are similar to other forms of spinal trauma and spinal cord injury. Below are some symptoms of spinal trauma:</P>\n<UL>\n<LI>Spinal shock — or the &quot;loss of feeling or movement below site of injury&quot; <A href=\"http://www.columbianeurosurgery.org/conditions/spinal-trauma/\" rel=\"noopener\" target=\"_blank\"><I>(Columbia University Medical Centre, 2016) </I></A>that can last between hours and weeks</LI>\n<LI>Loss of bladder or bowel function</LI>\n<LI>Difficulty breathing</LI>\n<LI>Muscle spasticity</LI>\n<LI>Difficulty understanding speech</LI>\n<LI>Problems with attention</LI>\n<LI>Memory challenges</LI>\n<LI>Heart rate and blood pressure problems</LI>\n</UL>\n<P>Unfortunately, it is sometimes challenging to identify which symptoms are due to a spinal contusion, and which ones are the result of a spinal cord injury directly. It can sometimes require a few days or weeks for the body to recover from spinal trauma and reveal if any permanent damage is left from the accident that caused the SCI.</P>\n<P>Understanding what a contusion is, and how it can come into play following a spinal cord injury is important in order to clearly appreciate your injury, understand your diagnoses, and work toward treatment and a prognosis. Doctors can sometimes use jargon that’s difficult to understand, so the more you can educate yourself about your condition, the more control you can have in your recovery and treatment.</P>\n<P>If you still have questions about the details of the spinal cord and how it may be affected from your injury, please contact us or download our <A href=\"/the-simplified-guide-to-understanding-a-spinal-cord-injury\" rel=\"noopener\" target=\"_blank\">guide to understanding a spinal cord injury</A>.",
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"description":"The spinal cord is a vital part of the human body. As the vehicle responsible for carrying messages from the brain to the rest of the body and back again, even the smallest interference can be detrimental. Following a traumatic spinal cord injury, this bundle of nerves can become bruised, also known as a contusion. Because of the nature of the nervous system, any interference can constitute a serious spinal contusion, but these facts will help you dissect all of the information from the medical professionals.

What Is a Spinal Contusion?
Signs-of-a-spinal-contusion-title-image
Much like any other bruise, a contusion can cause bleeding from local blood vessels and inflammation which, rather unlike bruises on other parts of the body, can have serious negative impacts on the spinal cord itself. Because the “blood must clot to stop the bleeding”a bruise results from contusions also increase cardiovascular risks.

For example, the swelling a contusion can cause will often disrupt nerve impulses that travel from the brain to the body through the spinal cord, and the severity of this will depend upon the level of injury. Unlike a concussion, a contusion would not cause unconsciousness or a ‘blackout’, but instead cause the patient to feel a numbness or tingling in the extremities.

A contusion can cause spinal compression, which happens when there is pressure on the spinal cord. This can go on to cause an array of physical symptoms such as loss of sensation in the feet, inability to use the hands and loss of sexual ability. It must be noted that not all contusions cause spinal compression, and not all spinal compression is caused by a contusion, although they do often connect this way.

Warning Signs of a Serious Spinal Contusion to Watch For
Firstly, doctors will try and establish what area or limb the injury has affected. Spinal contusions most often “affect the upper extremities bilaterally and also sometimes involve the lower extremities,” according to Dr. Wong, an orthopedic physician.

Symptoms include “numbness, tingling, [or] electric shock-like sensations and burning in the extremities,” (American Association of Neurological Surgeons, 2016). Generally falling into the category of “spinal trauma” there are many symptoms which are similar to other forms of spinal trauma and spinal cord injury. Below are some symptoms of spinal trauma:

Spinal shock — or the loss of feeling or movement below site of injury (Columbia University Medical Centre, 2016) that can last between hours and weeks
Loss of bladder or bowel function
Difficulty breathing
Muscle spasticity
Difficulty understanding speech
Problems with attention
Memory challenges
Heart rate and blood pressure problems
Unfortunately, it is sometimes challenging to identify which symptoms are due to a spinal contusion, and which ones are the result of a spinal cord injury directly. It can sometimes require a few days or weeks for the body to recover from spinal trauma and reveal if any permanent damage is left from the accident that caused the SCI.

Understanding what a contusion is, and how it can come into play following a spinal cord injury is important in order to clearly appreciate your injury, understand your diagnoses, and work toward treatment and a prognosis. Doctors can sometimes use jargon that’s difficult to understand, so the more you can educate yourself about your condition, the more control you can have in your recovery and treatment.

If you still have questions about the details of the spinal cord and how it may be affected from your injury, please contact us or download our guide to understanding a spinal cord injury.",
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